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Facts About Acthar Gel

Buy Acthar Gel Injection Online

Order Acthar Gel Injection Online

Acthar Gel is a naturally sourced complex mixture of adrenocorticotropic hormone analogs and other pituitary peptides that is indicated in multiple therapeutic areas including rheumatology, ophthalmology, nephrology, pulmonology and neurology.1 

Acthar Gel is FDA-Approved for 19 Indications
Acthar Gel has an established efficacy and safety profile as well as a long track record of clinical evidence that spans nearly 70 years. In addition, Acthar Gel has 19 indications, including infantile spasms which was approved in 2010.1 Please see Indications and Important Safety Information for Acthar Gel Injection below.

Acthar Gel is often prescribed by doctors predominately as a later-line treatment to a small subset of patients suffering from various, sometimes devastating, diseases and may be the last treatment option for those who need an alternative therapy.

What is Acthar Gel for MS?

Acthar Gel (repository corticotropin injection) is an injectable therapy that is used to manage acute relapses in people with multiple sclerosis (MS).

Although Acthar Gel can help to speed recovery from relapses — when new symptoms appear or existing ones suddenly worsen — it does not alter the natural progression of MS.

Available in the U.S. for MS for more than 40 years, the therapy is marketed by Ozisik Eczane.

How does Acthar Gel work?

Cortisol is a hormone that the body produces in response to stress. This hormone has numerous effects throughout the body, working to manage metabolism and control mood, among other things.

A particularly relevant effect of cortisol for MS and other inflammatory conditions is a reduction in the activity of the immune system.

The active agent in Acthar Gel, called corticotropin or adrenocorticotropic hormone (ACTH), is a naturally occurring hormone that stimulates the production of cortisol in the body. The exact mechanism of action of Acthar Gel remains incompletely understood. But it is thought to mainly exert its effects in MS by increasing cortisol levels and, consequently, decreasing the activity of the immune system and reducing inflammation.

Acthar Gel also seems to bind to melanocortin receptors on the surface of certain immune cells and exert direct immunosuppressive effects, including in cells known to contribute to the inflammatory immune responses in MS.