Polynucleotides Gone Wrong: Side Effects You Should Know

While polynucleotides are celebrated for their skin-rejuvenating effects—boosting hydration, encouraging collagen and cell repair—they’re not without risk. Common side effects include redness, mild swelling, bruising, tenderness, and small bumps.

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Polynucleotides are becoming increasingly popular in aesthetics for their ability to improve skin texture, hydration, and elasticity by stimulating natural repair processes. However, like any cosmetic treatment, they may sometimes cause unwanted side effects. Mild issues such as redness, swelling, or bruising at the injection site are common and usually temporary. In rare cases, patients may experience uneven results, lumps, or prolonged discomfort if the treatment is not performed correctly. This is why choosing a qualified medical professional is crucial. Understanding the risks helps ensure safe, effective, and natural-looking results with polynucleotide treatments.