Antidiabetic drugs pharmacology pdf

Antidiabetic drugs pharmacology pdf

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Mostly anti-diabetic drugs are administered orally except the insulin, exenatide, and pramlintide Additionally, the population of patients studied can impact the efficacy of a particular class of drug The American Diabetes Association/European Association for the Study of Diabetes consensus report “Management of Hyperglycemia in TypeDiabetes, ” and the update (35,) recommend a patient-centered approach to choosing appropriate pharmacologic treatment of blood glucose Classical antidiabetic agents (sulphonylureas, metformin, insulin) are now in competition with new glucose-lowering medications. People with Type1 Diabetes must always have a constant source of exogenous insulin, otherwise diabetic ketoacidosis (DKA) will result. Classical antidiabetic agents (sulphonylureas, metformin, insulin) are now in competition with new glucose-lowering medications. Gliclazide and Pharmacology can be divided into pharmacodynamics, the effect a drug has on the body, and pharmacokinetics, the study of what the body does to the drug, and both will be In this mini review, we endeavor to outline the current management principles, including the spectrum of medications that are currently used for pharmacologic management, for Pharmacologic Therapy for TypeDiabetes. Alpha-glucosidase inhibitors and overview of all the available oral antidiabetic drugs according to the different classes, their mechanisms of action and pharmacological profiles, and to assist Understand the different treatment options for patients with diabetes mellitus; explore the mechanisms of action of different antidiabetic drugs; understand the different types of Non Insulin Antidiabetic Drugs For treatment of patients who have TypeDiabetes but cannot be managed by diet alone. A combination of hypoglycemic drugs with or without Gliclazide, glibenclamide, glimepiride and glipizide are the most commonly used sulphonylureas in the UK, stimulating insulin secretion for hours. RecommendationsMost people with typediabetes should be treated with multiple daily injections of prandial and basal insulin, Key points. People with TypeDiabetes Three types of anti-diabetic drugs are discussed) Drugs that enhance insulin secretion like sulfonylureas and meglitinide analogues) Biguanides like metformin that Herein we propose to discuss the different classes of antidiabetic drugs available, their applications and mechanisms of action, particularly those of the newer and/or most widely prescribed These results indicate that comparing efficacies among different anti-diabetic medications is challenging, when the baseline HbA1c is different in the studies being compared. Alpha-glucosidase inhibitors and thiazolidinediones (glitazones) were not able to replace older agents, because of insufficient efficacy and/or poor tolerability/safety overview of all the available oral antidiabetic drugs according to the different classes, their mechanisms of action and pharmacological profiles, and to assist Anti-diabetic drugs treat diabetes mellitus by lowering glucose levels in the blood.